
Thermo Fisher Scientific COPS5 Monoclonal Antibody (OTI2B12), TrueMAB
COPS5 단일클론 항체(OTI2B12)는 인간 JAB1 단백질을 인식하며 WB, IHC, ICC/IF에 사용 가능. 마우스 IgG1 형식의 TrueMAB으로 고순도 친화 크로마토그래피 정제. 동결건조 형태로 보존 용이하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B12 |
| Immunogen | Full length human recombinant protein of human COPS5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
JAB-1 is a 38 kDa coactivator for cJUN and a component of the large protein complex known as the Signalosome, which plays a signaling role in mammalian cells.
This complex is analogous to the COP9 complex in plants, involved in light-mediated development.
JAB-1 has been implicated in targeting proteins for degradation via the proteasome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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