Thermo Fisher Scientific FMR1 Monoclonal Antibody (OTI1H9), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

FMR1 binds RNA and is associated with polysomes. It may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR normally occurs at 6–53 copies, but expansion to 55–230 repeats causes fragile X syndrome. Expansion of this repeat may also lead to premature ovarian failure. Multiple alternatively spliced transcript variants encoding different isoforms have been described, localized to distinct cellular compartments.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.