Thermo Fisher Scientific FMR1 Monoclonal Antibody (OTI1H9), TrueMAB
FMR1 단백질을 인식하는 Mouse Monoclonal Antibody로, Western blot 및 유세포 분석에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 인간 단백질에 특이적이며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 36–279 of human FMR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
FMR1 binds RNA and is associated with polysomes. It may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR normally occurs at 6–53 copies, but expansion to 55–230 repeats causes fragile X syndrome. Expansion of this repeat may also lead to premature ovarian failure. Multiple alternatively spliced transcript variants encoding different isoforms have been described, localized to distinct cellular compartments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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