Thermo Fisher Scientific TRAF3IP2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1–3 µg/mL

Product Specifications

Product Specific Information

• This antibody is expected to recognize reported isoforms 2 and 3 (NP_679211.1; NP_001157753.1).
• Tested in Peptide ELISA: antibody detection limit dilution 1:2,000.

Target Information

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals, and stress. The gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein-encoding transcripts, suggesting it has a regulatory role.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.