Thermo Fisher Scientific BCL6 Recombinant Rabbit Monoclonal Antibody (6E3)
BCL6 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 인간 시료 반응성, IHC, Flow Cytometry, ELISA 등 다양한 응용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관. 연구용 전용 시약.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6E3 |
| Immunogen | A synthesized peptide derived from Human BCL6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092537 |
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas, and Bcl-6 rearrangements have been detected in 33%–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas, and in nodular, lymphocyte predominant Hodgkin's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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