Thermo Fisher Scientific TIMM50 Polyclonal Antibody
Human TIMM50 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TIM50. Recombinant protein control fragment (Product #RP-103257). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648469 |
Product Specific Information
Immunogen sequence:
TGWRFKKRPG IETLFQQLAP LYEIVIFTSE TGMTAFPLID SVDPHGFISY RLFRDATRYM DGHHVKDISC LNRDPARVVV VDC
Highest antigen sequence identity to orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme encoded by the TIMM50 gene in humans. Tim50 is a subunit of the Tim23 translocase complex located in the inner mitochondrial membrane. Mutations in TIMM50 can result in epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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