Thermo Fisher Scientific C8A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human Complement component C8 alpha chain protein (310-460AA) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C8A,uniProtId:P07357-1,ncbiNodeId:9606,antigenRange:310-460,antigenLength:584,antigenImageFileName:PA5-144217_C8A_P07357-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144217_C8A_P07357-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.44 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_3091552

Target Information

C8A is a component of the complement system and contains three polypeptide subunits: alpha, beta and gamma. C8A, in particular, contains the alpha subunit of C8 and is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Disease associated with C8A include Type 1 C8 deficiency and immunodeficiency due to C8A deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.