Thermo Fisher Scientific DPM1 Polyclonal Antibody
Human DPM1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 기반 버퍼에 보관. 연구용으로만 사용하며, 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DPM1. Recombinant protein control fragment (Product #RP-99290). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640768 |
Product Specific Information
- Immunogen sequence:
SLEVSRSPRR SRRELEVRSP RQNKYSVLLP TYNERENLPL IVWLLVKSFS ESGINYEIII IDDGSPDGTR DVAEQLEKIY GSD - Highest antigen sequence identity to orthologs:
Mouse - 78%, Rat - 81%
Target Information
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER).
Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins.
Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase.
Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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