Thermo Fisher Scientific POLR1D Polyclonal Antibody
Human POLR1D 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 보존. RNA polymerase 복합체 연구 및 Treacher Collins syndrome 관련 연구용에 적합.
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Thermo Fisher Scientific POLR1D Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POLR1D. Recombinant protein control fragment (Product #RP-98005). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645752 |
Product Specific Information
Immunogen sequence:
EAKRGKTRAE TMGPMGWMKC PLASTNKRFL INTIKNTLPS HKEQDHEQKE GDKEPAKSQA QKEENPKKHR SHPYKHSFRA RGSASYSPPR KRSSQDKYEK RS
Antigen sequence identity (orthologs):
- Mouse: 77%
- Rat: 80%
Target Information
The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively.
Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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