Thermo Fisher Scientific TANK Polyclonal Antibody
TANK 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 인간 반응성, 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- PA585541
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TANK Polyclonal Antibody
Applications
Tested Application
- Western Blot (WB)
Tested Dilution
- 1:1,000–1:20,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human TANK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792681 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Rhesus Monkey (95%), Bovine (86%).
- Positive Control: human colon.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families leads to the formation of a TRAF/TANK complex that mediates activation of NF-kappa-B through association with kinases IKK-iota and TBK1. These proteins can form a complex with NEMO, regulating Ikappa-B activity. This suggests that TBK1 and IKK-iota may help modulate NF-kappa-B transactivation functions. At least two isoforms of TANK are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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