Thermo Fisher Scientific NUBP1 Polyclonal Antibody
Human NUBP1 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보존됩니다. 세포 내 Fe/S 단백질 조립 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NUBP1. Recombinant protein control fragment (Product # RP-98658) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644848 |
Product Specific Information
Immunogen sequence:
TSDEHLSVVR YLATAHIDGA VIITTPQEVS LQDVRKEINF CRKVKLPIIG VVEN
Sequence identity to orthologs:
- Mouse: 89%
- Rat: 89%
Target Information
NUBP1 is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery, required for the maturation of extramitochondrial Fe-S proteins.
The NUBP1–NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
It is implicated in the regulation of centrosome duplication and negatively regulates cilium formation and structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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