Thermo Fisher Scientific DR3 Recombinant Superclonal Antibody (11HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Cat, Pig, Sheep, and Bovine.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies, providing both polyclonal sensitivity and monoclonal specificity with consistent recombinant production.
Unlike traditional polyclonal antibodies, Superclonal™ antibodies have a defined mixture of light and heavy chains, ensuring reproducibility across lots.
Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. The product performance remains unchanged.

Target Information

DR3/TNFRSF25 is a member of the TNF-receptor superfamily, expressed mainly in lymphocyte-rich tissues. It plays a role in lymphocyte homeostasis, NF-kappa B activation, and apoptosis regulation.
Signal transduction involves adaptor proteins containing death domains. Mouse knockout studies suggest its role in removing self-reactive T cells in the thymus.
Multiple alternatively spliced transcript variants exist, encoding distinct isoforms, many of which are secreted. In activated B and T cells, splicing shifts toward producing full-length, membrane-bound isoforms, implicated in lymphocyte proliferation control.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.