Thermo Fisher Scientific NRGN Polyclonal Antibody
NRGN 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 인간, 마우스, 랫트 시료에 반응. 액상 형태로 1 mg/mL 농도, -20°C 보관. 신경 특이 단백질 연구용으로 적합.
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- PA5115645
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NRGN (Accession Q92686), corresponding to amino acid residues M1–R43 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900280 |
Product Specific Information
Antibody detects endogenous levels of total Neurogranin.
Target Information
Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. Exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated sequences. It is suggested that NRGN is a direct target for thyroid hormone in the human brain, and control of its expression may underlie the effects of hypothyroidism on mental states during development and adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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