Thermo Fisher Scientific TAS2R4 Polyclonal Antibody
TAS2R4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 인간 및 비인간 영장류 반응성을 가지며, 합성 펩타이드 항원을 사용했습니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific TAS2R4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TAS2R4 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TAS2R4.
Target Information
This gene encodes a member of the candidate taste receptor family, belonging to the G protein-coupled receptor superfamily. It is expressed specifically in taste receptor cells of the tongue and palate epithelia.
The gene is intronless and encodes a 7-transmembrane receptor protein functioning as a bitter taste receptor. It is clustered with three other candidate taste receptor genes on chromosome 7 and is genetically linked to loci influencing bitter perception.
TAS2R4 acts as a gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil, implicated in bitter compound perception in the oral cavity and gastrointestinal tract. It signals through PLCB2 and TRPM5 and is expressed exclusively in gustducin-positive taste receptor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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