Thermo Fisher Scientific ESRRA Polyclonal Antibody
ESRRA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, IP, ChIP 등 다양한 응용에 적합. 인간, 생쥐, 랫드 반응성 확인. 고순도 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific ESRRA Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:100–1:500 |
| ChIP assay (ChIP) | 2.5 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of Human ERR alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.32 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546225 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, Mouse kidney, Rat kidney, A549
- Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Pig (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of the estrogen receptor. ERR1 binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3', and can interact with the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1. ERR1 acts as an important regulator of MCAD promoter and functions as a metabolic regulator, often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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