Thermo Fisher Scientific SSTR3 Polyclonal Antibody
SSTR3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC에 사용 가능. Human 시료에 반응하며, 합성 펩타이드 면역원 기반. -20°C 보관, sodium azide 함유. 연구용 전용 제품.
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- PA3110
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500 | - |
| Immunocytochemistry (ICC/IF) | 1:5,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C Q(385) E R P P S R V A(393) of human SSTR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2302616 |
Product Specific Information
PA3-110 detects the Somatostatin Receptor 3 (SSTR3) in human samples.
It has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry.
In Western blot analysis of SSTR3-transfected HEK-293 cells, this antibody detects a ~60–70 kDa protein representing SSTR3.
The immunogen is a synthetic peptide corresponding to residues C Q(385) E R P P S R V A(393) of human SSTR3.
Target Information
Somatostatin Receptor Type 3 (SSTR3) is expressed in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, characterized by seven membrane-spanning helices and existing in both active and inactive forms.
Activation of GPCRs triggers signaling via G-proteins and downstream effectors, while regulatory mechanisms modulate receptor activity.
These pathways are of major pharmacological interest, with GPCR-targeted drugs such as Zyprexa and Claritin demonstrating significant clinical and commercial success.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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