Thermo Fisher Scientific alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (JF0980)
Recombinant rabbit monoclonal antibody targeting alpha Actinin 2 (JF0980). Validated for WB and IHC applications. High specificity to human, mouse, and rat samples. Supplied in liquid form with 1 mg/mL concentration and Protein A purification.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JF0980 |
| Immunogen | Synthetic peptide within human Alpha Actinin 2 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898961 |
Target Information
Alpha actinins belong to the spectrin gene superfamily, a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
- In nonmuscle cells: localized along microfilament bundles and adherens-type junctions, binding actin to the membrane.
- In muscle cells (skeletal, cardiac, smooth): localized to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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