Thermo Fisher Scientific CD36 Monoclonal Antibody (OTI3F4), TrueMAB
CD36 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. 인간 시료에 반응하며, Lyophilized 형태로 제공. 지질대사 및 염증 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F4 |
| Immunogen | Full length human recombinant protein of human CD36 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD36, also known as scavenger receptor class B member 3, is a surface protein expressed on macrophages, platelets, and adipocytes. It plays roles in lipid metabolism, inflammation, and atherosclerosis, mediating recognition and uptake of oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 acts as a receptor for thrombospondin and collagen, and is involved in cytoadherence of Plasmodium falciparum-infected erythrocytes. Mutations in CD36 can cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants exist.
Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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