Thermo Fisher Scientific CD3 epsilon Polyclonal Antibody, FITC
FITC로 결합된 Rabbit Polyclonal CD3 epsilon 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 고순도 친화 크로마토그래피 정제 및 안정적 보관용 버퍼 포함. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 150–200 of human CD3 epsilon protein |
| Conjugate | FITC (Excitation/Emission: 498/517 nm) |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD3 subunit complex is crucial in transducing antigen-recognition signals into T cells and regulating the surface expression of the TCR complex. T cell activation involves CD3 gamma, delta, epsilon, and zeta subunits, which are structurally related members of the immunoglobulin superfamily encoded on human chromosome 11.
CD3 plays roles in TCR-induced growth arrest, cell survival, and proliferation. The CD3 antigen is expressed on most peripheral blood lymphocytes and thymocytes but not on B or NK cells.
Defects in the CD3 gene are associated with CD3 immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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