Thermo Fisher Scientific CD3 Gamma Polyclonal Antibody
Rabbit polyclonal antibody recognizing human and mouse CD3 gamma protein. Suitable for WB, ELISA, and IP applications. Affinity purified and supplied in liquid form with BSA and glycerol. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 131–181 of human T-cell surface glycoprotein CD3 gamma protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.
This complex plays an important role in coupling antigen recognition to intracellular signal transduction pathways.
The genes encoding the epsilon, gamma, and delta polypeptides are located in the same cluster on chromosome 11.
Defects in the CD3G gene are associated with T cell immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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