
Thermo Fisher Scientific ATF Polyclonal Antibody
Human ATF2 인식하는 rabbit polyclonal antibody로, ICC/IF 등 다양한 응용에 적합. 보존제가 없는 액상 형태로 제공되며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
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Thermo Fisher Scientific ATF Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 1:300–1:10,000
Publications: - [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human ATF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788384 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human ATF2.
Target Information
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins.
ATF-2 interacts with various viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways.
Cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulates ATF-2 transcriptional activity.
Activation occurs via phosphorylation of Thr69 and Thr71 by SAPK and p38 MAPK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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