Thermo Fisher Scientific NAPEPLD Monoclonal Antibody (OTI5F7), TrueMAB
인간 NAPEPLD 단백질을 인식하는 단클론 항체로 Western blot, IHC, ICC/IF, Flow Cytometry에 적합. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 저장 버퍼 구성. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F7 |
| Immunogen | Full length human recombinant protein of human NAPEPLD produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme that releases endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues.
NAPE-PLD is expressed by specific populations of neurons in the brain and targeted to axonal processes.
NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules regulating postsynaptic neuron activity.
Additionally, NAPE-PLD catalyzes hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in rodents by prolonging latency to feed and postmeal interval.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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