Thermo Fisher Scientific NMT2 Monoclonal Antibody (OTI2B4), TrueMAB
인간 NMT2 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 IHC(P) 적용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적 보관을 위한 PBS/BSA/glycerol buffer 포함. 연구용 전용.
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Thermo Fisher Scientific NMT2 Monoclonal Antibody (OTI2B4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B4 |
| Immunogen | Full-length human recombinant NMT2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteolytic degradation maintains appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, receptor modulation, cell cycle regulation, transcription, and signaling.
The ubiquitin-proteasome pathway deconstructs most cytosolic and nuclear proteins, while others are degraded via vacuolar pathways including endosomes, lysosomes, and endoplasmic reticulum.
The 26S proteasome is an ATP-dependent, multisubunit molecular machine (~2.5 MDa) composed of a 20S proteolytic core and 19S regulatory subunits. The 19S complex recognizes ubiquitinated proteins and assists in unfolding and translocation into the 20S lumen.
Defects in this pathway are linked to genetic diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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