Thermo Fisher Scientific Cholera Toxin beta Polyclonal Antibody
콜레라 독소 베타 서브유닛을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. ELISA에 적합하며 정제된 콜레라지노이드로부터 유래. 비결합형 액상 형태로 제공되며, 4-5 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
- ELISA: 1:1,000 희석 비율
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified Choleragenoid |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4–5 mg/mL |
| Purification | IgG fraction |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_779810 |
Product Specific Information
PA1-25635 detects cholera toxin from bacterial samples.
Target Information
Cholera toxin (CTX, Ctx, or CT) is a protein complex secreted by Vibrio cholerae, the causative agent of cholera infection.
The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge, and activates adenylate cyclase in intestinal mucosa cells, increasing intracellular cAMP levels.
The beta subunit binds to the GM1-ganglioside receptor, initiating toxin action and facilitating uptake of the alpha subunit into cells.
The holotoxin consists of a pentameric ring of beta subunits surrounding the alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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