Thermo Fisher Scientific RASAL1 Polyclonal Antibody
RASAL1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 최적화. 항원 친화 크로마토그래피로 정제된 액상 시약으로 1 mg/mL 농도. 인간 시료 반응성, 연구용 전용 제품.
- 카탈로그번호
- A305-876A
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RASAL1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:10,000–1:25,000
- Immunoprecipitation (IP): 50–100 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 754 and 804 of human RasGAP-activating-like protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins, resulting in the inactive GDP-bound form of RAS and allowing control of cellular proliferation and differentiation.
This family member is strongly and selectively expressed in endocrine tissues and contains domains characteristic of the GAP1 subfamily of RasGAP proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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