Thermo Fisher Scientific MYBBP1A Polyclonal Antibody
Thermo Fisher Scientific의 MYBBP1A Polyclonal Antibody는 Mouse MYBBP1A 단백질을 인식하는 Rabbit IgG 항체입니다. Western Blot 및 IHC에 사용 가능하며, Protein A로 정제된 액상 형태입니다. PBS buffer에 보관하며 -20°C에서 안정적으로 저장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.25 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of mouse MYBBP1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691403 |
Product Specific Information
This target displays homology in the following species:
- Guinea Pig: 83%
- Mouse: 100%
- Rat: 92%
Target Information
The Myb family of transcription factors, including A-, B-, and c-Myb, regulate differentiation, cellular growth, and gene expression.
c-Myb is essential for controlling hematopoietic cell proliferation and differentiation, with levels decreasing upon terminal differentiation.
MYBBP1A (Myb-binding protein 1A) is a nuclear protein localized mainly in nucleoli. It interacts with c-Myb and other transcription factors, including AhR, enhancing AhR-dependent gene expression.
MYBBP1A negatively regulates PPAR gamma coactivator 1 alpha (PGC-1 alpha) through p38 MAPK and functions as a nucleocytoplasmic shuttling protein utilizing both CRM1-dependent and independent export pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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