Thermo Fisher Scientific Periplakin Polyclonal Antibody
Human Periplakin 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P)에서 1:5,000~1:10,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 40% 글리세롤 포함. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPL. Recombinant protein control fragment (Product #RP-98660). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645828 |
Product Specific Information
Immunogen sequence:
LLAGLDKVAS DLDRQEKAIT GILRPPLEQG RAVQDSAERA KDLKNITNEL LRIEPEKTRS TAEGEAFIQA LPGSGTTPLL RTRVEDTNRK YEHLL
Sequence identity:
- Mouse: 85%
- Rat: 84%
Target Information
The protein encoded by this gene is a component of desmosomes and the epidermal cornified envelope in keratinocytes. The N-terminal domain interacts with the plasma membrane, and the C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. It may act as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a kinase involved in cell growth and survival signaling, interacts with this protein, suggesting a role in AKT1-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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