Thermo Fisher Scientific H3F3A Polyclonal Antibody
Human Histone H3.3A 특이적 Rabbit Polyclonal Antibody로 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 고품질 액상 시약. PBS/glycerol buffer로 안정화되어 장기 보관 가능. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Histone H3.3 (Product #RP-104343) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642452 |
Product Specific Information
- Immunogen sequence: SEAYLVGLFE DTNLCAIHAK RVTIM
- Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
Post-translational modifications of histones alter chromatin structure or facilitate transcription factor binding. The N-terminal tail of histone H3 can undergo methylation, acetylation, or phosphorylation, affecting various cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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