Thermo Fisher Scientific KCNJ10 Monoclonal Antibody (1C11)
KCNJ10(Kir4.1) 단백질을 인식하는 Mouse Monoclonal Antibody(클론 1C11). Western blot 및 ELISA에 적합하며, Human 시료에 반응. PBS(pH 7.4) 용액 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C11 |
| Immunogen | KCNJ10 (NP_002232, 276–379 a.a.) partial recombinant protein with GST tag (GST MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
DFELVLILSG TVESTSATCQ VRTSYLPEEI LWGYEFTPAI SLSASGKYIA DFSLFDQVVK VASPSGLRDS TVRYGDPEKL KLEESLREQA EKEGSALSVR ISNV
Target Information
The KIR (inwardly rectifying potassium channel) family allows potassium ions to flow preferentially into the cell.
KIR4.1 (Kir1.2) is highly expressed in the brain, including glial cells, astrocytes, and cortical neurons. It is also found in myelin-producing oligodendrocytes and is essential for myelination during nervous system development.
The human KIR4.1 gene maps to chromosome 1.
KIR4.2 (Kir1.3) is expressed in kidney, lung, heart, thymus, and thyroid during development and maps to chromosome 21, possibly associated with Down syndrome pathogenesis.
KIR5.1 forms functional channels only when coexpressed with KIR4.1 or KIR4.2 in kidney and pancreas.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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