Thermo Fisher Scientific ACVR2A Monoclonal Antibody (149/1)
ACVR2A 단백질을 검출하는 Thermo Fisher Scientific의 Mouse IgG1 단클론 항체입니다. Western blot, ICC/IF, IP 등 다양한 응용에 사용 가능하며, 비결합형 액상 형태로 제공됩니다. 인간 Activin receptor type II에 특이적이며 연구용으로 적합합니다.
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Thermo Fisher Scientific ACVR2A Monoclonal Antibody (149/1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 149/1 |
| Immunogen | Recombinant intracellular kinase domain of the human type 2 activin receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1954793 |
Product Specific Information
MA1-91751 detects Activin receptor type II from human samples.
Target Information
Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases.
ACVR2A is involved in the activin and myostatin signaling pathway.
Aliases: ACVR2, ACTRII
These receptors are transmembrane proteins composed of:
- A ligand-binding extracellular domain with cysteine-rich region
- A transmembrane domain
- A cytoplasmic domain with predicted serine/threonine specificity
Type I receptors are essential for signaling, while type II receptors are required for ligand binding and expression of type I receptors.
After ligand binding, type I and II receptors form a stable complex, leading to phosphorylation of type I receptors by type II receptors.
Type II receptors are considered constitutively active kinases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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