Thermo Fisher Scientific LYK5 Polyclonal Antibody
LYK5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간 및 생쥐 반응성 우수. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
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Thermo Fisher Scientific LYK5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–215 of Human LYK5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546070 |
Product Specific Information
- Recommended positive controls: 293T, HepG2, mouse brain
- Predicted reactivity: Human (98%), Mouse (95%), Rat (94%), Chicken (90%), Sheep (95%), Chimpanzee (98%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LYK5 (STE20-related Adaptor Protein, STRAD; FLJ90524)
Gene Map Locus: 17q23.3
Members of the STE-20 like kinase family stimulate MAPK pathways by activating MAPKKK. STRAD is a pseudokinase with a STE-20-like domain lacking catalytic residues. It binds LKB1, regulating its tumor suppressor activity and subcellular localization. STRAD-LKB1 interaction promotes phosphorylation of STRAD and enhances LKB1 autophosphorylation.
Safety Information
⚠ WARNING: This product contains mercury, known to cause birth defects or reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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