Thermo Fisher Scientific Briakinumab Recombinant Human Monoclonal Antibody
Recombinant human monoclonal antibody targeting IL-12 and IL-23 for research use. High purity and low endotoxin level (<0.01 EU/µg). Suitable for ELISA and immunological studies. Supplied as liquid form, unconjugated, stored at -20°C.
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- MA541782
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Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Human / IgG1, lambda |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human IL12B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.68 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2910925 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Briakinumab is a human anti-IL-12 monoclonal antibody developed for research related to T-cell driven autoimmune diseases. It targets and neutralizes interleukin-12 and interleukin-23, two inflammation-associated proteins such as pro-inflammatory interleukins or tumor necrosis factor-alpha. Briakinumab represents a novel approach to studying psoriasis, multiple sclerosis, Crohn’s disease, and other autoimmune and inflammatory disorders.
As of 2011, pharmaceutical development for psoriasis has been discontinued in the U.S. and Europe.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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