Thermo Fisher Scientific Defensin 1/3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

3-6 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (DESLAPKHPGSRKN) corresponding to the internal amino acids of DEFA1/3 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Defensin 1/3,uniProtId:P59665-1,ncbiNodeId:9606,antigenRange:50-63,antigenLength:94,antigenImageFileName:PA5-19228_Defensin_13_P59665-1_Goat.svg,antigenImageFileNamePDP:PA5-19228_Defensin_13_P59665-1_Goat_PDP.jpeg,sortOrder:1},{targetFamily:Defensin 1/3,uniProtId:P59666-1,ncbiNodeId:9606,antigenRange:50-63,antigenLength:94,antigenImageFileName:PA5-19228_Defensin_13_P59666-1_Goat.svg,antigenImageFileNamePDP:PA5-19228_Defensin_13_P59666-1_Goat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_11009371

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Target Information

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.