Thermo Fisher Scientific DCAF7 Polyclonal Antibody
DCAF7 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF, ELISA 등에 사용 가능. 사람, 생쥐, 랫트 반응성. Rabbit IgG 기반, 액상 형태로 친화 크로마토그래피 정제. 세포질 및 핵 위치 단백질 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–342 of human DCAF7 (NP_005819.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806677 |
Product Specific Information
- Immunogen sequence:
MSLHGKRKEI YKYEAPWTVY AMNWSVRPDK RFRLALGSFV EEYNNKVQLV GLDEESSEFI CRNTFDHPYP TTKLMWIPDT KGVYPDLLAT SGDYLRVWRV GETETRLECL LNNNKNSDFC APLTSFDWNE VDPYLLGTSS IDTTCTIWGL ETGQVLGRVN LVSGHVKTQL IAHDKEVYDI AFSRAGGGRD MFASVGADGS VRMFDLRHLE HSTIIYEDPQ HHPLLRLCWN KQDPNYLATM AMDGMEVVIL DVRVPCTPVA RLNNHRACVN GIAWAPHSSC HICTAADDHQ ALIWDIQQMP RAIEDPILAY TAEGEINNVQ WASTQPDWIA ICYNNCLEIL RV - Positive Samples: 293T
- Cellular Location: Cytoplasm, Nucleus
Target Information
WD-repeats are motifs found in many proteins, characterized by a conserved core of 40–60 amino acids forming a propeller-like tertiary structure. Proteins containing WD-repeats are involved in chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis, and vesicular trafficking.
WDR68 (also known as DCAF7, HAN11, or WD repeat-containing protein 68) is a 342 amino acid protein belonging to the WD repeat DCAF7 family, containing 4 WD repeats. It localizes to the cytoplasm and nucleus, participates in protein modification and ubiquitination pathways, and interacts directly with Dyrk1A, Dyrk1B, and Dia1. WDR68 plays roles in craniofacial and skin development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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