Thermo Fisher Scientific CD200 Recombinant Rabbit Monoclonal Antibody (002)
Recombinant Rabbit Monoclonal Antibody specific to Mouse CD200. Validated for Flow Cytometry (1:25–1:100). Produced in HEK293 cells, purified via Protein A. Supplied as 1 mg/mL liquid in PBS without preservative. Store at 4 °C short term or −20 °C long...
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Applications
- Flow Cytometry (Flow): Tested dilution 1:25–1:100
- Refer to publications for additional validation data.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 002 |
| Immunogen | Recombinant Mouse CD200 protein (50074-M08H) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866651 |
Additional Formats
Target Information
CD200 is a type‑1 membrane glycoprotein with two immunoglobulin domains, belonging to the immunoglobulin superfamily. It is broadly distributed on cell surfaces and interacts with CD200R on myeloid cells to inhibit macrophage activation. Homologues are found in many herpesviruses and poxviruses. Studies in mouse and rat suggest CD200 regulates myeloid cell activity and provides inhibitory signals to macrophage lineages. Multiple alternatively spliced transcript variants exist, encoding different isoforms. CD200 dysfunction has been associated with Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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