Thermo Fisher Scientific PLAU Monoclonal Antibody (OTI5H4), TrueMAB
Human PLAU 단백질을 인식하는 Mouse monoclonal 항체로 Western Blot과 IHC(Paraffin)에 적합. 고순도 Affinity chromatography 정제, 1 mg/mL 농도의 액상 형태. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적. 연구용으로만 사용.
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- TA805243
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 107–379 of human PLAU produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and decreased affinity for fibrin binding.
This protein converts plasminogen to plasmin by cleavage of an Arg-Val bond. Plasmin then cleaves this protein at a Lys-Ile bond to form a two-chain derivative (HMW-uPA). HMW-uPA can be further processed into LMW-uPA, which remains proteolytically active but does not bind to the uPA receptor.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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