Thermo Fisher Scientific EMX2 Monoclonal Antibody (4D8)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

4D8

Immunogen

EMX2 (NP_004089, 103 a.a. approximately 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EMX2,uniProtId:Q04743-1,ncbiNodeId:9606,antigenRange:103-200,antigenLength:252,antigenImageFileName:H00002018-M02_EMX2_Q04743-1_House_mouse.svg,antigenImageFileNamePDP:H00002018-M02_EMX2_Q04743-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: HSPHPLFASQ QRDPSTFYPW LIHRYRYLGH RFQGNDTSPE SFLLHNALAR KPKRIRTAFS PSQLLRLEHA FEKNHYVVGA ERKQLAHSLS LTETQVKV

Target Information

This gene encodes a homeobox-containing transcription factor that is the homolog to the empty spiracles gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.