Thermo Fisher Scientific EMX2 Monoclonal Antibody (4D8)

Applications

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
HSPHPLFASQ QRDPSTFYPW LIHRYRYLGH RFQGNDTSPE SFLLHNALAR KPKRIRTAFS PSQLLRLEHA FEKNHYVVGA ERKQLAHSLS LTETQVKV

Target Information

This gene encodes a homeobox-containing transcription factor that is the homolog to the empty spiracles gene in Drosophila.
Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenital system.
It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas.
It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation.
In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10.
Alternative splicing results in multiple transcript variants encoding distinct proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.