Thermo Fisher Scientific Human ESRP2 Synthetic Peptide
Human ESRP2 단백질의 카복시 말단 근처 17아미노산 서열을 기반으로 한 합성 펩타이드. RBM35B/ESRP2 관련 항체의 차단용으로 사용 가능. 고순도 정제, 액상 형태, PBS 버퍼 보존. 연구용으로만 사용.
- 카탈로그번호
- PEP1224
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to a 17 amino acid peptide near the carboxy terminus of human RBM35B.
PEP-1224 can be used as a blocking peptide with polyclonal antibody PA5-21110.
Target Information
RBM35A, also known as ESRP2, is an mRNA splicing factor that, together with its related protein RBM35A (ESRP1), coordinates an epithelial cell-type-specific splicing program.
Both RBM35B and RBM35A are involved in posttranscriptional regulation of genes such as FGFR2, CD44, CTNND1, and ENAH by influencing protein translation via 5′ UTRs of mRNAs.
These proteins are global regulators of an epithelial regulatory network. Loss of this ESRP-regulated splicing program induces epithelial-mesenchymal transition-related morphological changes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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