Thermo Fisher Scientific BAG1 Monoclonal Antibody (2D3)
BAG1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상형 항체이며, PBS(pH 7.4) buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D3 |
| Immunogen | BAG1 (NP_004314, 241–345 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
EKIADQLEEL NKELTGIQQG FLPKDLQAEA LCKLDRRVKA TIEQFMKILE EIDTLILPEN FKDSRLKRKG LVKKVQAFLA ECDTVEQNIC QETERLQSTN FALAE
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis (programmed cell death). The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene (BAG1). It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.
At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site and alternative downstream AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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