Thermo Fisher Scientific BAD Polyclonal Antibody, MaxPab
BAD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 in situ PLA에 적합. Human 시료 반응성, PBS buffer 기반 액상 형태. 세포 사멸 연구 및 BCL-2 family 단백질 분석에 활용 가능.
- 카탈로그번호
- H00000572-D01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
in situ PLA (PLA)
- Tested Dilution: 1:1200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | BAD (NP_004313.1, 1–168 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MFQIPEFEPS EQEDSSSAER GLGPSPAGDG PSGSGKHHRQ APGLLWDASH QQEQPTSSSH HGGAGAVEIR SRHSSYPAGT EDDEGMGEEP SPFRGRSRSA PPNLWAAQRY GRELRRMSDE FVDSFKKGLP RPKSAGTATQ MRQSSSWTRV FQSWWDRNLG RGSSAPSQ
Target Information
The protein encoded by BAD is a member of the BCL-2 family, which regulates programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, inhibiting their anti-apoptotic activity. Its proapoptotic function is controlled by phosphorylation through kinases such as AKT and MAPK, and by the phosphatase calcineurin. Alternative splicing generates two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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