Thermo Fisher Scientific HLCS Polyclonal Antibody
Human HLCS 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HLCS. Recombinant protein control fragment (Product #RP-91775) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642466 |
Product Specific Information
Immunogen sequence:
DLPYDYSSSL ESVADETSPE REGRRVNLTG KAPNILLYVG SDSQEALGRF HEVRSVLADC VDIDSYILYH LLEDSALRDP WTDNCLLLVI ATRESIPEDL YQKFMAYLSQ GGKVLGLSSS FTFGGFQV
Highest antigen sequence identity to the following orthologs:
- Mouse: 74%
- Rat: 73%
Target Information
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and three other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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