Thermo Fisher Scientific Plexin-A1 Monoclonal Antibody (8A10A6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

8A10A6

Immunogen

Purified recombinant fragment of human PLXNA1 (AA: 1100-1200) expressed in E. coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Plexin-A1,uniProtId:Q9UIW2-1,ncbiNodeId:9606,antigenRange:1100-1200,antigenLength:1896,antigenImageFileName:MA5-31856_Plexin-A1_Q9UIW2-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31856_Plexin-A1_Q9UIW2-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787479

Product Specific Information

MA5-31856 has been tested in indirect ELISA.

Target Information

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.