Thermo Fisher Scientific IARS2 Polyclonal Antibody
Human IARS2 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 보존액에 40% 글리세롤 포함. 연구용으로만 사용 가능하며 장기 보관 시 -20°C 권장.
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Applications
- Western Blot (WB): 0.04–0.4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IARS2. Recombinant protein control fragment (Product # RP-94009) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642605 |
Product Specific Information
- Immunogen sequence:
NVIHPDVVVN GGQDQSKEPP YGADVLRWWV ADSNVFTEVA IGPSVLNAAR DDISKLRNTL RFLLGNVADF NPETDSIPVN DMYV - Ortholog sequence identity:
Mouse – 79%, Rat – 77%
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is associated with genetic alterations and thyroid hormone response abnormalities. Trip230 interacts with Rb and thyroid hormone receptor (TR) through distinct domains. Complex formation with Rb occurs in a hormone-independent manner, while complex formation with TR is thyroid hormone-dependent. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting phosphorylation is important for nuclear translocation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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