Thermo Fisher Scientific AP3M1 Polyclonal Antibody
AP3M1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot과 Immunohistochemistry에 사용 가능하며, 인간·마우스·랫트 반응성을 가집니다. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 안정적 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human AP3M1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154319 |
Product Specific Information
- Suggested positive control: human brain tissue lysate
- PA5-21162 can be used with blocking peptide PEP-1276.
Target Information
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2), and a small adaptin (APS1 or AP3S2).
This complex is associated with the Golgi region and peripheral structures, facilitating vesicle budding from the Golgi membrane and trafficking to lysosomes.
AP3M1 is highly homologous to AP3M2 but preferentially binds the YQRL motif from the cytosolic domain of TGN38.
It also interacts with the HIV-1 virulence protein Nef.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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