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Thermo Fisher Scientific TMEM88 Polyclonal Antibody
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TMEM88 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 Wnt 신호전달 관련 연구에 활용 가능합니다.
- 카탈로그번호
- PA521164
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 07:58
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific PA521164 TMEM88 Polyclonal Antibody 100 ug pk판매 단위 pk ·
재고 확인 필요
689,200원VAT 포함 758,120원
Thermo Fisher Scientific · Thermo Fisher Scientific TMEM88 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid peptide near the carboxy terminus of human TMEM88 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153618 |
Product Specific Information
- Suggested positive control: human brain tissue lysate
- PA5-21164 can be used with blocking peptide PEP-1278
Target Information
Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail binds the PDZ domain of Dishevelled (Dvl), a key component in Wnt signaling pathways.
TMEM88 attenuates Wnt/β-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner. Knockdown of TMEM88 by RNAi increases Wnt activity, suggesting that TMEM88 regulates Wnt signaling in a context-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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