
Thermo Fisher Scientific RAD54B Polyclonal Antibody
RAD54B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간 반응성 확인, 항원 친화 크로마토그래피로 정제. 연구용으로 DNA 복구 및 재조합 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 580–865 of Human RAD54B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545353 |
Product Specific Information
- Recommended positive controls: Molt-4
- Predicted reactivity: Mouse (88%), Rat (84%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The RAD54B protein belongs to the DEAD-like helicase superfamily and shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, which are involved in homologous recombination and DNA repair. This protein binds to double-stranded DNA and exhibits ATPase activity in the presence of DNA. It is highly expressed in testis and spleen, suggesting active roles in meiotic and mitotic recombination. Homozygous mutations have been observed in primary lymphoma and colon cancer.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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