Thermo Fisher Scientific Integrin beta 7 Polyclonal Antibody
Integrin beta 7 단백질 검출용 Thermo Fisher Scientific 폴리클로날 항체. 인간 및 생쥐 반응성, Western blot에 적합. 고순도 친화 크로마토그래피 정제, PBS/glycerol 저장용액, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ITGB7 (Accession P26010), corresponding to amino acid residues P504–S554 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852345 |
Product Specific Information
Antibody detects endogenous levels of total ITGB7.
Target Information
Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin (LPAM-1), expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin (HML-1), expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes.
Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1, and fibronectin, while the ligand of HML-1 is E-cadherin (CD324).
Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells, promoting transmigration of leukocytes to extravascular spaces during the inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-102971_Integrin_beta_7_P26010-1_Rabbit.svg, PA5-102971_Integrin_beta_7_P26010-1_Rabbit_PDP.jpeg)
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