Thermo Fisher Scientific TENM2 Polyclonal Antibody
Rabbit polyclonal antibody against human TENM2 protein. Suitable for research use in neural development and cell adhesion studies. Supplied as an unconjugated liquid form with 0.05 mg/mL concentration. Store at 4°C short term or -20°C long term.
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Thermo Fisher Scientific TENM2 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TENM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664925 |
Product Specific Information
Immunogen sequence:
ASIREKAGHWF ATTTPIIGKG IMFAIKEGRV TTGVSSIASE DSRKVASVLN NAYYLDKMHY SIEGKDTHYF VKIGSADGDL VTLGTTIG
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
TENM2 is involved in neural development, regulating the establishment of proper connectivity within the nervous system. It promotes the formation of filopodia and enlarged growth cones in neuronal cells, and induces homophilic cell-cell adhesion.
May function as a cellular signal transducer. Isoform 2 acts as a ligand of the ADGRL1 receptor, mediating axon guidance and heterophilic cell-cell adhesion.
Ten-2 intracellular domain induces gene transcription inhibition.
{ECO:0000269 PubMed:21724987}, {ECO:0000250}
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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