Thermo Fisher Scientific Kappa Light Chain Recombinant Rabbit Monoclonal Antibody (JE56-54)
인간 IgG의 카파 경쇄를 인식하는 재조합 토끼 단일클론 항체입니다. Western blot과 파라핀 조직 면역조직화학(IHC)에 적합합니다. Protein A로 정제되었으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE56-54 |
| Immunogen | Full length native human IgG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931362 |
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure consisting of two heavy chains (five types) and two light chains (kappa, lambda; both ~22.5 kDa).
Kappa and lambda chains have variable and constant regions, distinguishable by antigenic properties of the constant region.
The kappa to lambda ratio is approximately 70:30.
Antibodies to the kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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