Thermo Fisher Scientific RAE1 Polyclonal Antibody
RAE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol 버퍼에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Thermo Fisher Scientific RAE1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–368 of human RAE1 (NP_0036011) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806650 |
Product Specific Information
Immunogen sequence:
MSLFGTTSGF GTSGTSMFGS ATTDNHNPMK DIEVTSSPDD SIGCLSFSPP TLPGNFLIAG SWANDVRCWE VQDSGQTIPK AQQMHTGPVL DVCWSDDGSK VFTASCDKTA KMWDLSSNQA IQIAQHDAPV KTIHWIKAPN YSCVMTGSWD KTLKFWDTRS SNPMMVLQLP ERCYCADVIY PMAVVATAER GLIVYQLENQ PSEFRRIESP LKHQHRCVAI FKDKQNKPTG FALGSIEGRV AIHYINPPNP AKDNFTFKCH RSNGTNTSAP QDIYAVNGIA FHPVHGTLAT VGSDGRFSFW DKDARTKLKT SEQLDQPISA CCFNHNGNIF AYASSYDWSK GHEFYNPQKK NYIFLRNAAE ELKPRNKKPositive Samples: Mouse brain, Mouse spleen, Mouse thymus, Rat brain
Cellular Location: Cytoplasm, Nucleus
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes result in accumulation of poly-containing mRNA in the nucleus, suggesting involvement in RNA export. The human RAE1 protein, homologous to yeast Rae1, contains four WD40 motifs and localizes to distinct foci in the nucleoplasm, nuclear rim, and cytoplasmic meshwork structures. It is involved in nucleocytoplasmic transport and may attach cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-93166_RAE1_P78406-1_Rabbit.svg, PA5-93166_RAE1_P78406-1_Rabbit_PDP.jpeg)
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