Thermo Fisher Scientific Tensin 1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Tensin 1. Recombinant protein control fragment (Product #RP-96508). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Tensin 1,uniProtId:Q9HBL0-3,ncbiNodeId:9606,antigenRange:537-621,antigenLength:1839,antigenImageFileName:PA5-57515_Tensin_1_Q9HBL0-3_Rabbit.svg,antigenImageFileNamePDP:PA5-57515_Tensin_1_Q9HBL0-3_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648379

Product Specific Information

Immunogen sequence: LSPLTNGLDK SYPMEPMVNG GGYPYESASR AGPAHAGHTA PMRPSYSAQE GLAGYQREGP HPAWPQPVTT SHYAHDPSGM FRSQS

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.

Target Information

Tensin is involved in the maintenance of cellular structure by anchoring Actin filaments at the focal adhesion via F-Actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine, and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.